{"id":10601,"date":"2026-04-15T10:07:40","date_gmt":"2026-04-15T10:07:40","guid":{"rendered":"https:\/\/akdenizolay.com.tr\/index.php\/2026\/04\/15\/gen-tedavisi-uyguladigimiz-bebek-bugun-27-yasinda\/"},"modified":"2026-04-15T10:07:42","modified_gmt":"2026-04-15T10:07:42","slug":"gen-tedavisi-uyguladigimiz-bebek-bugun-27-yasinda","status":"publish","type":"post","link":"https:\/\/akdenizolay.com.tr\/index.php\/2026\/04\/15\/gen-tedavisi-uyguladigimiz-bebek-bugun-27-yasinda\/","title":{"rendered":"\u201cGen Tedavisi Uygulad\u0131\u011f\u0131m\u0131z Bebek, Bug\u00fcn 27 Ya\u015f\u0131nda\u201d"},"content":{"rendered":"

Ac\u0131badem \u00dcniversitesi, ge\u00e7ti\u011fimiz g\u00fcnlerde \u00e7ocuk imm\u00fcnolojisi, gen tedavisi ve a\u015f\u0131lar alan\u0131nda d\u00fcnyan\u0131n en sayg\u0131n isimlerinden biri olan Prof. Dr. Alain Fischer\u2019i a\u011f\u0131rlad\u0131. Hen\u00fcz 6 ayl\u0131kken \u00f6l\u00fcmc\u00fcl bir ba\u011f\u0131\u015f\u0131kl\u0131k sistemi hastal\u0131\u011f\u0131na yakalanan bir bebe\u011fi gen tedavisiyle tedavi ederek t\u0131p tarihinde \u00e7\u0131\u011f\u0131r a\u00e7an Prof. Dr. Alain Fischer, bug\u00fcn 27 ya\u015f\u0131nda sa\u011fl\u0131kl\u0131 bir ya\u015fam s\u00fcren bu hastan\u0131n hik\u00e2yesiyle modern t\u0131bb\u0131n ula\u015ft\u0131\u011f\u0131 noktay\u0131 g\u00f6zler \u00f6n\u00fcne seriyor\u2026<\/strong><\/em><\/p>\n

Ac\u0131badem \u00dcniversitesi Molek\u00fcler Biyoloji ve Genetik B\u00f6l\u00fcm\u00fc Ba\u015fkan\u0131 Prof. Dr. Batu Erman\u2019\u0131n ev sahipli\u011finde \u00fcniversitede konferans veren Prof. Dr. Alain Fischer bilim d\u00fcnyas\u0131nda \u00e7\u0131\u011f\u0131r a\u00e7an \u00e7al\u0131\u015fmalar\u0131n\u0131 ve t\u0131bb\u0131n gelece\u011fine y\u00f6n veren geli\u015fmeleri kat\u0131l\u0131mc\u0131larla payla\u015ft\u0131. Pediatrik imm\u00fcnoloji, nadir hastal\u0131klar ve gen tedavileri alan\u0131ndaki \u00f6nc\u00fc \u00e7al\u0131\u015fmalar\u0131yla tan\u0131nan Prof. Dr. Alain Fischer, \u00f6zellikle ba\u011f\u0131\u015f\u0131kl\u0131k sistemi hastal\u0131klar\u0131n\u0131n genetik temellerinin anla\u015f\u0131lmas\u0131 ve tedavi edilmesine y\u00f6nelik ara\u015ft\u0131rmalar\u0131yla modern t\u0131pta \u00f6nemli bir d\u00f6n\u00fc\u015f\u00fcm\u00fcn mimarlar\u0131 aras\u0131nda yer al\u0131yor. Prof. Dr. Alain Fischer, gen tedavilerinin sundu\u011fu umut verici geli\u015fmelerin yan\u0131 s\u0131ra a\u015f\u0131lar\u0131n toplum sa\u011fl\u0131\u011f\u0131 a\u00e7\u0131s\u0131ndan vazge\u00e7ilmez rol\u00fcn\u00fc g\u00fc\u00e7l\u00fc mesajlarla vurguluyor\u2026\u00a0<\/strong><\/em><\/p>\n

Ziyareti kapsam\u0131nda Ac\u0131badem \u00dcniversitesi Molek\u00fcler Biyoloji ve Genetik B\u00f6l\u00fcm\u00fc laboratuvarlar\u0131n\u0131 da gezen ve burada y\u00fcr\u00fct\u00fclen h\u00fccresel tedavi \u00e7al\u0131\u015fmalar\u0131 hakk\u0131nda bilgi alan Prof. Dr. Alain Fischer; CAR-T h\u00fccreleriyle uygulanan kanser tedavisinin, yani\u00a0hastan\u0131n kendi ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccrelerinin laboratuvarda g\u00fc\u00e7lendirilip yeniden v\u00fccuda verilerek kanser h\u00fccrelerini daha etkili \u015fekilde yok etmesini sa\u011flayan bu yenilik\u00e7i yakla\u015f\u0131m\u0131n, yak\u0131n gelecekte \u00e7ok daha yayg\u0131nla\u015faca\u011f\u0131n\u0131 ifade ediyor. Prof. Dr. Alain Fischer, ayn\u0131 zamanda gen ve a\u015f\u0131 politikalar\u0131 alan\u0131nda toplum sa\u011fl\u0131\u011f\u0131na \u00f6nemli katk\u0131lar sunan bir bilim insan\u0131 olarak, bu alandaki \u00e7al\u0131\u015fmalar\u0131n stratejik \u00f6nemine de dikkat \u00e7ekiyor\u2026<\/strong><\/em><\/p>\n

40 y\u0131ld\u0131r genetik hastal\u0131klar\u0131n izini s\u00fcrd\u00fc\u011f\u00fcn\u00fc belirten Prof. Dr. Alain Fischer, meslek hayat\u0131n\u0131 b\u00fcy\u00fck \u00f6l\u00e7\u00fcde ba\u011f\u0131\u015f\u0131kl\u0131k sistemine ba\u011fl\u0131 nadir hastal\u0131klar\u0131n ara\u015ft\u0131r\u0131lmas\u0131na adad\u0131\u011f\u0131n\u0131 s\u00f6yl\u00fcyor: \u201c500\u2019\u00fcn \u00fczerinde farkl\u0131 hastal\u0131ktan s\u00f6z ediyoruz. Bu hastal\u0131klar\u0131n tamam\u0131 genetik bozukluklar ve mutasyonlar nedeniyle ortaya \u00e7\u0131k\u0131yor. 40 y\u0131l\u0131 a\u015fk\u0131n s\u00fcredir bu hastal\u0131klar\u0131n genetik nedenlerini anlamaya ve tedavi yollar\u0131 geli\u015ftirmeye \u00e7al\u0131\u015f\u0131yorum.\u201d<\/p>\n

Genetik ve molek\u00fcler biyolojide ya\u015fanan geli\u015fmelerin t\u0131pta adeta bir devrim yaratt\u0131\u011f\u0131n\u0131 ifade eden Prof. Dr. Alain Fischer, \u201cDNA analizleri sayesinde art\u0131k genlerdeki bozukluklar\u0131 tespit edebiliyor, hastal\u0131klar\u0131n mekanizmas\u0131n\u0131 daha iyi anlayabiliyor ve \u00e7ok daha etkili tedavi y\u00f6ntemleri geli\u015ftirebiliyoruz\u201d \u015feklinde konu\u015fuyor.\u00a0<\/p>\n

6 Ayl\u0131kken Gen Tedavisi Uyguland\u0131, Bug\u00fcn 27 Ya\u015f\u0131nda Sa\u011fl\u0131kl\u0131 Bir Birey<\/strong><\/p>\n

Bug\u00fcne kadar gen tedavisiyle sa\u011fl\u0131klar\u0131na kavu\u015fturdu\u011fu bir\u00e7ok \u00e7ocuktan s\u00f6z eden Prof. Dr. Alain Fischer, gen tedavilerinin somut ba\u015far\u0131s\u0131na dikkat \u00e7ekerek a\u011f\u0131r ba\u011f\u0131\u015f\u0131kl\u0131k yetmezli\u011fi (SCID) hastal\u0131\u011f\u0131yla do\u011fan bir bebe\u011fin hikayesini payla\u015f\u0131yor:\u00a0<\/p>\n

\u201cSCID hastas\u0131 bebekler\u00a0\u00e7ok az veya hi\u00e7 ba\u011f\u0131\u015f\u0131kl\u0131k sistemi olmadan d\u00fcnyaya gelirler. \u2018<\/em>Balon \u00c7ocuk Hastal\u0131\u011f\u0131\u2019 olarak da bilinen bu \u00e7ocuklar\u00a0tedavi edilmezlerse genellikle do\u011fumdan sonra ilk y\u0131l i\u00e7inde hayatlar\u0131n\u0131 kaybederler. Ancak\u00a0erken te\u015fhis ve uygun tedaviyle bu \u00e7ocuklar ya\u015fayabilir. Biz\u00a01999 y\u0131l\u0131nda, hen\u00fcz 6 ayl\u0131k bir bebe\u011fe gen tedavisi uygulad\u0131k. Bug\u00fcn o hasta 27 ya\u015f\u0131nda ve sa\u011fl\u0131kl\u0131 bir ya\u015fam s\u00fcr\u00fcyor. Bu, gen tedavilerinin ne kadar g\u00fc\u00e7l\u00fc bir tedavi y\u00f6ntemi oldu\u011funun en \u00e7arp\u0131c\u0131 g\u00f6stergelerinden biri.\u201d<\/p>\n

Gen tedavileriyle genetik hastal\u0131klar\u0131 tedavi etmeye odakland\u0131klar\u0131n\u0131 s\u00f6yleyen Prof. Dr. Alain Fischer, \u201cGen tedavilerinde hedefimiz bozuk olan geni d\u00fczeltmek oldu. Yakla\u015f\u0131k 30 sene \u00f6nce insan h\u00fccresine sa\u011fl\u0131kl\u0131, normal bir genin kopyas\u0131n\u0131 koyarak bozuk genleri tedavi etme yakla\u015f\u0131m\u0131n\u0131 geli\u015ftirdik.\u00a0Bug\u00fcne kadar da yakla\u015f\u0131k 60 hastay\u0131 gen tedavisiyle iyile\u015ftirdik\u201d \u015feklinde konu\u015fuyor. Prof. Dr. Alain Fischer, bu y\u00f6ntemin yaln\u0131zca ba\u011f\u0131\u015f\u0131kl\u0131k sistemi hastal\u0131klar\u0131nda de\u011fil; karaci\u011fer, g\u00f6z ve sinir sistemi hastal\u0131klar\u0131 gibi pek \u00e7ok genetik rahats\u0131zl\u0131kta da etkili sonu\u00e7lar verdi\u011fini vurguluyor.<\/p>\n

\u201cGen Tedavisi T\u0131bb\u0131n Gelece\u011finde Kritik Bir Yer Tutacak\u201d<\/strong><\/p>\n

Gen tedavilerinin mevcut tedavi y\u00f6ntemlerinin yerini tamamen almayaca\u011f\u0131n\u0131 ancak onlar\u0131 tamamlayan en \u00f6nemli yakla\u015f\u0131mlardan biri olaca\u011f\u0131n\u0131 belirten Prof. Dr. Alain Fischer, \u201cGen tedavileri \u00f6zellikle genetik hastal\u0131klarda en \u00f6nemli tedavi se\u00e7eneklerinden biri haline gelecek. Gelecekte \u00e7ok daha yayg\u0131n kullan\u0131laca\u011f\u0131n\u0131 \u00f6ng\u00f6r\u00fcyoruz\u201d diyor.\u00a0<\/p>\n

Bilimsel geli\u015fmelerin h\u0131z kesmeden devam etti\u011fini ifade eden Prof. Dr. Alain Fischer, erken tan\u0131 teknolojileri sayesinde gelecekte hastal\u0131klar\u0131n daha anne karn\u0131nda tespit edilerek do\u011fumdan hemen sonra tedavi edilebilece\u011fini de s\u00f6zlerine ekliyor: \u201cGelecekte \u00f6zellikle nadir ve genetik hastal\u0131klarda \u00f6nemli geli\u015fmeler olacak. Gen tedavileri pek \u00e7ok hastal\u0131\u011fa \u00e7are olacak. Ayr\u0131ca k\u00f6k h\u00fccre tedavileri de \u00f6n planda olacak. \u00d6zellikle gen tedavileri ve k\u00f6k h\u00fccre tedavilerinin geli\u015ftirilmesiyle g\u00fcn\u00fcn birinde t\u00fcm genetik hastal\u0131klara tedavi bulaca\u011f\u0131z. Bilimsel \u00e7al\u0131\u015fmalar umut vaat ediyor. Ayr\u0131ca erken tan\u0131 y\u00f6ntemleri de giderek geli\u015fiyor. Gelecekte pek \u00e7ok hastal\u0131\u011fa anne karn\u0131nda tan\u0131 koyabilece\u011fiz. Genetik bilimindeki geli\u015fmeler sayesinde bug\u00fcn art\u0131k anne karn\u0131ndaki bebe\u011fin DNA\u2019s\u0131n\u0131, t\u00fcm genetik yap\u0131s\u0131n\u0131 inceleyebiliyoruz. \u00c7ocuk do\u011far do\u011fmaz tan\u0131 koyabilmemiz sayesinde \u00e7ok erken bir d\u00f6nemde tedaviye ba\u015flam\u0131\u015f oluyoruz\u2026\u201d\u00a0<\/p>\n

Prof. Dr. Alain Fischer, bilimin gelece\u011finde yapay zeka ve geneti\u011fin \u201cel ele\u201d oldu\u011funa dikkat \u00e7ekiyor. Bilimsel ara\u015ft\u0131rmalarda yapay zekan\u0131n rol\u00fcne de de\u011finen Prof. Dr. Alain Fischer, \u201cYapay zeka, ara\u015ft\u0131rmalar\u0131n kalitesini art\u0131ran \u00e7ok g\u00fc\u00e7l\u00fc bir ara\u00e7. Genetik ve biyomedikal \u00e7al\u0131\u015fmalarla birlikte kullan\u0131ld\u0131\u011f\u0131nda \u00e7ok daha h\u0131zl\u0131 ve do\u011fru sonu\u00e7lara ula\u015fmam\u0131z\u0131 sa\u011fl\u0131yor\u201d ifadelerini kullan\u0131yor.\u00a0<\/p>\n

\u201cA\u015f\u0131lar T\u0131bb\u0131n En B\u00fcy\u00fck Ba\u015far\u0131lar\u0131ndan Biri\u201d<\/strong><\/p>\n

Fransa\u2019n\u0131n \u201ca\u015f\u0131 el\u00e7isi\u201d olarak bilinen Prof. Dr. Alain Fischer, a\u015f\u0131lar\u0131n halk sa\u011fl\u0131\u011f\u0131 a\u00e7\u0131s\u0131ndan kritik \u00f6nemine dikkat \u00e7ekiyor. Prof. Dr. Alain Fischer, \u201c20 y\u0131l \u00f6nce Fransa\u2019da a\u015f\u0131 oranlar\u0131 biraz d\u00fc\u015fm\u00fc\u015ft\u00fc. Bunun \u00fczerine o d\u00f6nemin Sa\u011fl\u0131k Bakan\u0131, a\u015f\u0131lanan \u00e7ocuk say\u0131s\u0131n\u0131 art\u0131rmak i\u00e7in neler yapmam\u0131z gerekti\u011fini benimle g\u00f6r\u00fc\u015fmek istemi\u015fti. A\u015f\u0131larla uzun y\u0131lard\u0131r \u00e7al\u0131\u015f\u0131yorum, bakanl\u0131klara dan\u0131\u015fmanl\u0131k yap\u0131yorum. Covid-19 salg\u0131n\u0131 d\u00f6neminde de bakanl\u0131klarla toplumun a\u015f\u0131lanmas\u0131 i\u00e7in \u00f6nemli \u00e7al\u0131\u015fmalar\u0131m\u0131z olmu\u015ftu.\u00a0A\u015f\u0131lar, \u00f6zellikle salg\u0131n hastal\u0131klar\u0131n \u00f6nlenmesinde en etkili ara\u00e7t\u0131r. Bir \u00e7ocuk imm\u00fcnolojisi uzman\u0131 olarak a\u015f\u0131lar\u0131n \u00f6nemini her zaman vurguluyorum. A\u015f\u0131lar t\u0131bb\u0131n en b\u00fcy\u00fck ba\u015far\u0131lar\u0131ndan biridir\u201d diyor.<\/p>\n

D\u00fcnya Sa\u011fl\u0131k \u00d6rg\u00fct\u00fc verilerine at\u0131fta bulunan Prof. Dr. Alain Fischer, \u201cSon 50 y\u0131lda k\u0131zam\u0131k, tetanoz ve Hepatit B gibi hastal\u0131klara kar\u015f\u0131 yap\u0131lan a\u015f\u0131lar sayesinde yakla\u015f\u0131k 150 milyon insan\u0131n hayat\u0131 kurtar\u0131ld\u0131. Covid-19 a\u015f\u0131lar\u0131 ise tek ba\u015f\u0131na yakla\u015f\u0131k 20 milyon insan\u0131n ya\u015fam\u0131n\u0131 kurtard\u0131\u201d bilgisini payla\u015f\u0131yor.\u00a0<\/p>\n

\u201cA\u015f\u0131 Kar\u015f\u0131tl\u0131\u011f\u0131 \u00c7ok Tehlikeli, Yanl\u0131\u015f Bilgilere \u0130nanmay\u0131n\u201d<\/strong><\/p>\n

A\u015f\u0131 kar\u015f\u0131tl\u0131\u011f\u0131na da de\u011finen Prof. Dr. Alain Fischer, bu yakla\u015f\u0131m\u0131n ciddi bir halk sa\u011fl\u0131\u011f\u0131 tehdidi olu\u015fturdu\u011funu belirterek, \u201cA\u015f\u0131lar\u0131n otizm ya da kalp hastal\u0131klar\u0131na yol a\u00e7t\u0131\u011f\u0131 y\u00f6n\u00fcndeki iddialar\u0131n hi\u00e7bir bilimsel dayana\u011f\u0131 yok. Bunlar\u0131n hepsi yalan haber. Bu yanl\u0131\u015f bilgilere inan\u0131lmas\u0131, ge\u00e7mi\u015fte kontrol alt\u0131na al\u0131nm\u0131\u015f hastal\u0131klar\u0131n yeniden ortaya \u00e7\u0131kmas\u0131na neden oluyor\u201d diyor.<\/p>\n

D\u00fcnya genelinde\u00a0\u00f6zellikle 2019 y\u0131l\u0131ndan bu yana\u00a0k\u0131zam\u0131k a\u015f\u0131s\u0131na eri\u015fimdeki aksakl\u0131klar ve a\u015f\u0131 kar\u015f\u0131tl\u0131\u011f\u0131n\u0131n artmas\u0131 nedeniyle \u00e7ocuk \u00f6l\u00fcmlerinde yeniden ciddi bir y\u00fckseli\u015f g\u00f6r\u00fcl\u00fcyor.\u00a0A\u015f\u0131 yapt\u0131r\u0131lmamas\u0131 nedeniyle \u00f6rne\u011fin k\u0131zam\u0131k gibi hastal\u0131klar\u0131n yeniden g\u00f6r\u00fcld\u00fc\u011f\u00fcn\u00fc vurgulayan Prof. Dr. Alain Fischer, \u201c2019\u2019dan bu yana baz\u0131 y\u0131llarda 100 bini a\u015fan say\u0131da \u00e7ocuk, k\u0131zam\u0131k nedeniyle hayat\u0131n\u0131 kaybetti. Oysa a\u015f\u0131yla bu \u00f6l\u00fcmler b\u00fcy\u00fck \u00f6l\u00e7\u00fcde \u00f6nlenebilir.\u00a0A\u015f\u0131 olmamak \u00e7ok ciddi ve tehlikeli sonu\u00e7lar do\u011furabilir\u201d \u015feklinde konunun ciddiyetine dikkat \u00e7ekiyor.<\/p>\n

\u00a0<\/p>\n

\u00a0<\/p>\n

Kaynak: (BYZHA) Beyaz Haber Ajans\u0131<\/p>\n","protected":false},"excerpt":{"rendered":"

Ac\u0131badem \u00dcniversitesi, ge\u00e7ti\u011fimiz g\u00fcnlerde \u00e7ocuk imm\u00fcnolojisi, gen tedavisi ve a\u015f\u0131lar alan\u0131nda d\u00fcnyan\u0131n en sayg\u0131n isimlerinden biri olan Prof.<\/p>\n","protected":false},"author":1,"featured_media":10602,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[23],"tags":[],"class_list":["post-10601","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik"],"_links":{"self":[{"href":"https:\/\/akdenizolay.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/10601","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/akdenizolay.com.tr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/akdenizolay.com.tr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/akdenizolay.com.tr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/akdenizolay.com.tr\/index.php\/wp-json\/wp\/v2\/comments?post=10601"}],"version-history":[{"count":1,"href":"https:\/\/akdenizolay.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/10601\/revisions"}],"predecessor-version":[{"id":10603,"href":"https:\/\/akdenizolay.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/10601\/revisions\/10603"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/akdenizolay.com.tr\/index.php\/wp-json\/wp\/v2\/media\/10602"}],"wp:attachment":[{"href":"https:\/\/akdenizolay.com.tr\/index.php\/wp-json\/wp\/v2\/media?parent=10601"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/akdenizolay.com.tr\/index.php\/wp-json\/wp\/v2\/categories?post=10601"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/akdenizolay.com.tr\/index.php\/wp-json\/wp\/v2\/tags?post=10601"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}